When studying brain tumors and what can be done in order to slow their progression, at the very least, certain drugs will be focused on. Some of these may have been utilized to help other conditions in the past while another group of drugs may be entirely unique. Whatever the case may be, it's apparent that some of them will leave greater impacts than others, not only in the medical field but amongst patients as well. Could a potential two-drug combination help to expand results even further?
YottaFire posted an article that spoke about a combination of drugs that could come into play in order to help stop the rate at which brain tumors progress. A study that was done featured a group of mice that was afflicted with the condition. With the usage of the drug tandem, it was found that their survival rates were made much better. This is reason enough why the study is worthy of the attention of organizations like Voices against Brain Cancer but what are the specifics behind it?
Dana-Farber Cancer Institute put together the study and it was determined that a combination of two drugs working together could play positively into the actions of glioblastoma. With this particular tandem, it would be able to focus on two cell signaling pathways. A previous study was done but it was deemed unsuccessful because of how only one pathway was focused on. While this improvement is worthy of note, what is more worthy has got to be a certain abnormality that is typical amongst one-third of glioblastoma patients.
The report talked about the loss of a gene referred to as PTEN. For those who are unaware, PTEN acts as a tumor-suppressing gene. If the PTEN gene is not seen, though, the body is met with a chain reaction that can cause overactive molecular growth signals which, in turn, can cause cells to grow at malignant rates until the activity eventually reaches the brain. With these drugs brought into effect, the gene in question is not replaced but rather the growth caused is blocked.
It's apparent that the human body goes about all types of actions, whether or not we know of them. It's clear that we won't be able to understand all of them but it is clear that they are carried out for certain reasons. For example, the lack of PTEN is one that can bring brain tumors to the surface. It's an unfortunate case to make but the truth of the matter is that there are certain drugs that can be utilized; it's just a matter of determining how effective they will be from one patient to the next.
YottaFire posted an article that spoke about a combination of drugs that could come into play in order to help stop the rate at which brain tumors progress. A study that was done featured a group of mice that was afflicted with the condition. With the usage of the drug tandem, it was found that their survival rates were made much better. This is reason enough why the study is worthy of the attention of organizations like Voices against Brain Cancer but what are the specifics behind it?
Dana-Farber Cancer Institute put together the study and it was determined that a combination of two drugs working together could play positively into the actions of glioblastoma. With this particular tandem, it would be able to focus on two cell signaling pathways. A previous study was done but it was deemed unsuccessful because of how only one pathway was focused on. While this improvement is worthy of note, what is more worthy has got to be a certain abnormality that is typical amongst one-third of glioblastoma patients.
The report talked about the loss of a gene referred to as PTEN. For those who are unaware, PTEN acts as a tumor-suppressing gene. If the PTEN gene is not seen, though, the body is met with a chain reaction that can cause overactive molecular growth signals which, in turn, can cause cells to grow at malignant rates until the activity eventually reaches the brain. With these drugs brought into effect, the gene in question is not replaced but rather the growth caused is blocked.
It's apparent that the human body goes about all types of actions, whether or not we know of them. It's clear that we won't be able to understand all of them but it is clear that they are carried out for certain reasons. For example, the lack of PTEN is one that can bring brain tumors to the surface. It's an unfortunate case to make but the truth of the matter is that there are certain drugs that can be utilized; it's just a matter of determining how effective they will be from one patient to the next.
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